Methods and compositions for treating skin

ABSTRACT

The present disclosure generally relates to methods and compositions for treating skin. In some embodiments, the method uses an exfoliation tool. In some embodiments, the method uses an exfoliation tool together with selected skin care agents or compositions.

CROSS-REFERENCE TO RELATED APPLICATIONS

This application is a continuation of U.S. patent application Ser. No. 16/040,582 filed Jul. 20, 2018, which is a divisional of U.S. patent application Ser. No. 14/835,806 filed Aug. 26, 2015, issued as U.S. Pat. No. 10,052,468, which is a continuation of U.S. patent application Ser. No. 13/248,367 filed Sep. 29, 2011, issued as U.S. Pat. No. 9,144,434, which claims benefit to U.S. Provisional Application No. 61/387,577 filed on Sep. 29, 2010, each of which are hereby incorporated by reference in their entireties.

FIELD

The present disclosure generally relates to methods and compositions for treating skin. In some embodiments, the method uses an exfoliation tool. In some embodiments, the method uses an exfoliation tool together with selected skin care agents or compositions.

BACKGROUND

Proper skin care is important for heath and cosmetic reasons. Skin is a vital organ and a breakdown in the skin can adversely affect the skin's function as a barrier and make it susceptible to infection. A breakdown in the skin can also be very painful, such as the case of excessive dry skin. Visual irregularities in the skin can adversely affect a person's confidence and other people's perceptions.

There remains a need for improved methods of treating skin and maintaining or improving its health and cosmetic features. It is against this background that the present disclosure is made.

SUMMARY

Surprisingly, it has been found that using an exfoliation tool together with selected skin care agents results in improved skin health and appearance.

Accordingly, in some embodiments, the present disclosure relates to a method of treating skin where a user applies a first skin care agent to skin and treats the skin with an exfoliation tool. In some embodiments, the method also includes additional skin care agents. In some embodiments, the method uses a specific treatment regimen.

In some embodiments, the present disclosure relates to a kit that includes an exfoliation tool and selected skin care agents. The kit can also include specific instructions that explain how to use the exfoliation tool and selected skin care agents.

Finally, in some embodiments, the present disclosure relates to methods of treating skin using an exfoliation tool and selected skin care compositions.

These and other embodiments will be apparent to those of skill in the art and others in view of the following detailed description. It should be understood, however, that this summary, and the detailed description illustrate only some examples of various embodiments, and are not intended to be limiting to the claimed invention.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 shows a view of the exfoliation tool.

FIG. 2 shows a close up of the exfoliation tool head, including the roller and the acupuncture needles.

FIG. 3 shows a person using the exfoliation tool on their face.

DETAILED DESCRIPTION

The present disclosure generally relates to skin treatment using an exfoliation tool and selected skin care agents. While not wanting to be bound by theory, it is believed that the combination of the exfoliation tool and the selected skin care agents increases the uptake of the selected skin care agents by the epidermis (outer layer of skin) than if the skin care agent was just placed on top of the epidermis. This is believed to be in part because the exfoliation tool increases the surface area of the epidermis by creating micro pores or holes in the skin, thereby allowing a greater number of skin cells on the epidermis to contact and benefit from the selected skin care agent. One result of this is that a user can see improved results in a shorter period of time.

The Exfoliation Tool

The exfoliation tool of the present disclosure is designed to create micro pores, channels, or holes in the epidermis or outer layer of the skin. In some embodiments, the exfoliation tool is a roller attached to a handle or wand, such as that shown in FIG. 1. FIG. 1 generally shows an exfoliation tool 10. The exfoliation tool 10 includes a handle or wand 12 and a head 14 attached to the handle 12. The head 14 includes a roller 16. The roller 16 is held in place by a U-shaped collar 18 that is attached to the handle or wand 12 and engages the roller 16 at either end in such a way that allows the roller 16 to rotate. The roller 16 includes a plurality of acupuncture needles 20. FIG. 1 shows the acupuncture needles 20 in rows, but it is understood that the needles may be arranged in a variety of configurations. The exfoliation tool 10 is preferably easily manufactured. In some embodiments, the handle 12, head 14, including the collar 18 and the roller 16 are injection molded plastic. The acupuncture needles 20 are preferably stainless steel, and more preferably surgical grade stainless steel.

FIG. 2 shows a close up of the head 14, including the collar 18, roller 16, and acupuncture needles 20. The acupuncture needles 20 preferably form micro holes, pores, or channels in the epidermis of the skin. It is understood that other structures may be used instead of acupuncture needles. When using acupuncture needles, the needles are preferably solid and made of stainless steel. The needles are preferably from about 0.1 mm to about 0.5 mm in length so that when the exfoliation tool is placed on skin and rolled using moderate pressure, the needles penetrate only the epidermis, and not the deeper layers of skin. In some embodiments, the needles do not penetrate more than about 100 microns to 500 microns into the epidermis.

FIG. 3 shows a person 22 using the exfoliation tool of FIG. 1 on their face. In some embodiments, the exfoliation tool can be scaled slightly smaller for use on the face or slightly larger for use on the body or scalp, reflecting the respective differences in surface area of the face versus the rest of the body or scalp. During use on the face, it may be beneficial to divide the face into sections such as the forehead, right side, left side, chin, and neck. A user may then roll the head of the exfoliation tool of FIG. 1 over each section using moderate pressure. In some embodiments, it may be beneficial for the user to change the rolling direction with each pass. A similar method can be used when treating other body parts or the scalp (i.e., dividing into sections and rolling the exfoliation tool over the various sections, changing the rolling direction from time to time).

Selected Skin Care Agents

The exfoliation tool may be used in conjunction with at least one skin care agent. The skin care agent is preferably an agent that helps maintain, treat, or improve the health or cosmetic appearance of skin. Exemplary skin care agents include the following: abrasives, antiacne agents, antidandruff agents, antifungal agents, antimicrobial agents, antioxidants, toners, moisturizers, skin conditioners, humectants, emollients, skin bleaching or lightening agents, proteins, cleaners, hair conditioners, and the like.

Abrasives may be used to remove unwanted skin such as dead skin cells and calluses. Exemplary abrasives include but are not limited to the following: alumina, aluminum silicate, apricot seed powder, attapulgite, avocado powder, bamboo powder, barley flour, bentonite, calcium carbonate, calcium phosphate, calcium pyrophosphate, calcium sulfate, chalk, chitin, coconut shell powder, colloidal oatmeal, comfrey leaf powder, corn cob meal or powder, corn flour, corn meal, corn starch, diamond powder, diatomaceous earth, dicalcium phosphate, dicalcium phosphate dehydrate, egg shell powder, Fuller's earth, hydrated silica, hydroxyapatite, kaolin, kiwi seed, lauryl acrylate polymers, loess, magnesium potassium fluorosilicate, magnesium trisilicate, microcrystalline cellulose, montmorillonite, Moroccan lava clay, oat bran, oat flour, oatmeal, oyster shell powder, peach pit powder, peanut flour, pecan shell powder, polyethylene, pumice, raspberry seed, rice bran, rye flour, sand, silica, sodium bicarbonate, sodium hydroxypropyl starch phosphate, sodium magnesium fluorosilicate, sodium silicoaluminate, soybean flour, sweet almond meal, talc, tin oxide, tricalcium phosphate, walnut shell powder, wheat bran, wheat flour, wheat powder, wheat starch, wood powder, zirconium silicate, and derivatives and combinations of these.

Antiacne agents may be used to treat blemishes, pimples, blackheads, and whiteheads. Exemplary antiacne agents include but are not limited to salicylic acid, benzoyl peroxide, or sulfur, and their derivatives and combinations.

Antidandruff agents may be used to treat dandruff, seborrheic dermatitis, or psoriasis. Exemplary antidandruff agents include but are not limited to the following: coal tar, salicylic acid, selenium sulfide, sulfur, zinc pyrithione, and their derivatives and combinations.

Antifungal agents include agents that inhibit the growth and reproduction of fungal cells or decreases the number of fungi present. Exemplary antifungal agents include but are not limited to the following: calcium undecylenate, ketoconazol, povidone-iodine (PVP-iodine), tea tree oil, undecylenic acid, zinc undecylenate, and their derivatives and combinations.

Antimicrobial agents include agents that kill microorganisms or prevent or inhibit microorganism growth and reproduction or agents that help prevent infection in minor cuts, scrapes, and burns. Exemplary antimicrobial agents include but are not limited to the following: lower chain (C1-C4) alcohols, quaternary ammonium compounds such as benzalkonium chloride and benzethonium chloride, clindamycin, methylbenzethonium chloride, hydrogen peroxide, Oligopeptide-10, phenols, tea tree oil, triclosan, povidone-iodine (PVP-Iodine), and their derivatives and combinations.

Antioxidants include agents that are characterized as free radical scavengers and help reverse skin damage caused by free radicals. Exemplary antioxidants include but are not limited to the following: acetyl cysteine, alpha lipoic acid, arbutin, ascorbic acid (vitamin C), ascorbic acid polypeptide, ascorbyl dipalmitate, ascorbyl methylsilanol pectinate, ascorbyl palmitate, ascorbyl stearate, BHA, BHT, t-butyl hydroquinone, caffeic acid, camellia sinensis oil, carotenoids, chitosan ascorbate, chitosan glycolate, chitosan salicylate, chlorogenic acids, CoQ10, cortisen, cysteine, cysteine HC1, decyl mercaptomethylimidazole, diamylhydroquinone, di-t-butylhydroquinone, dicetyl thiodipropionate, dicyclopentadiene/t-butylcresol copolymer, digalloyl trioleate, dilauryl thiodipropionate, dimyristyl thiodipropionate, dioleyl tocopheryl methylsilanol, diosmine, disodium ascorbyl sulfate, disodium rutinyl disulfate, distearyl thiodipropionate, ditridecyl thiodipropionate, dodecyl gallate, dunaliella salina extract, erythorbic acid, ethyl ferulate, ferulic acid, hydroquinone, p-hydroxyanisole, hydroxylamine HC1, hydroxylamine sulfate, hydroxytyrosol, isooctyl thioglycolate, isoquercitrin, kojic acid, madecassicoside, magnesium ascorbate, magnesium ascorbyl phosphate, melatonin, methoxy-PEG-7 rutinyl succinate, methylene di-t-butylcresol, methylsilanol ascorbate, nordihydroguaiaretic acid, octyl gallate, phenylthioglycloic acid, phloroglucinol, potassium ascorbyl tocopheryl phosphate, potassium sulfite, propyl gallate, resveratrol, rosmarinic acid, rutin, sirtunis, sodium ascorbate, sodium ascorbyl/cholesteryl phosphate, sodium bisulfite, sodium erythorbate, sodium metabisulfite, sodium sulfite, sodium thioglycolate, sorbityl furfural, tea tree oil, tetrahexyldecyl ascorbate, tetrahydrodiferuloylmethane, thiodiglycol, thiodiglycolamide, thiodiglycolic acid, thioglycolic acid, thiolactic acid, thiosalicylic acid, thiotaurine, tocophereth derivatives, tocopherol (vitamin E), tocophersolan, tocopheryl acetate, tocopheryl linoleate, tocopherol linoleate/oleate, tocopheryl nicotinate, tocopheryl succinate, tocoquinone, o-tolyl biguanide, tri(nonylphenyl)phosphate, ubiquinone, vitamin D, zinc dibutyldithiocarbamate, and their derivatives and combinations.

Toners include agents that create a tightening or tingling sensation on skin. Exemplary toners include but are not limited to the following: alcohol derivatives such as denatured alcohol and SD alcohol, aluminum derivatives such as aluminum acetate, aluminum bromohydrate, aluminum chloride, aluminum chlorohydrex, aluminum citrate, aluminum diacetate, aluminum dichlorohydrate, aluminum dichlorohydrex, aluminum glycinate, aluminum lactate, aluminum phenolsulfonate, aluminum sesquichlorohydrate, aluminum sesquichlorohydrex, and aluminum sulfate, aluminum zirconium derivatives such as aluminum zirconium octachlorohydrex, aluminum zirconium pentachlorohydrate, aluminum zirconium pentachlorohydrex, aluminum zirconium tetrachlorohydrate, aluminum zirconium tetrachlorohydrex, aluminum zirconium trichlorhydrate, and aluminum zirconium trichlorohydrex, ammonium alum, calcium chloride, calcium lactate, dimethyl MEA, gallic acid, lens esculenta (lentil) seed extract, potassium alum, sodium alum, sodium aluminum chlorohydroxy lactate, sodium aluminum lactate, tannic acid, tioxolone, tranexamic acid, zinc acetate, zinc chloride, zinc lactate, zinc phenolsulfonate, zinc sulfate, zirconium chlorohydrate, witch hazel, and their derivatives and combinations.

Skin conditioning agents or moisturizers can be classified into different groups such as emollients, humectants, and occlusive agents. Emollients include agents that remain on the upper layers of skin and act as lubricants and improve appearance. Exemplary emollients include but are not limited to the following: lanolin, glycerides, fruit oils, nut oils, vegetable oils, dimethicones, methicone, cyclomethicone, dormin, fatty acids, myristate derivatives like butyl myristate and myristyl myristate, oleate derivates, C1-C4 glycols, fatty acid glycols, glycol esters, glycerine, glycerols, paraffin, rapeseed oil, long chain alcohols, olive oil, jojoba oil, castor oil, and their derivatives and combinations. Humectants include agents that increase the water content of the top layer of skin. Exemplary humectants include but are not limited to the following: allatoin, agarose, arginine, benzyl hyaluronate, chitosan, copper, corn glycerides, gluconolactone, lactic acid, lactobionic acid, lactose, lysine, kombucha, maltitol, maltose, mannitol, propylene glycol, sodium aspartate, fructose, honey, glycerin, hydroxyethyl urea, and their derivatives and combinations. Occlusive agents slow the evaporation of water from skin. Exemplary occlusive agents include but are not limited to the following: petrolatum, shea butter, dimethicones, plant and animal oils such as avocado, canola, cod liver, and corn, mineral oil, olive oil, soybean oil, lanolin, glycerides, beeswax, triglycerides, long chain fatty alcohols, coco butter, coconut oil, jojoba oil, propylene glycol and their derivatives and combinations.

In addition to skin conditioning agents that provide a moisturizing benefit, there are other skin conditioning agents that improve the appearance of skin. Exemplary skin conditioning agents include but are not limited to the following: cholesterol, cystine, hyaluronic acid, keratin, egg yolk, glycine, gluconolactone, lactic acid, lactobionic acid, panthenol, retinol, salicylic acid, vegetable oil, proteins, vitamins, bisabolol, ceramide, coenzyme A, lecithin and their derivatives and combinations.

Skin bleaching or lightening agents include agents that lighten pigment in skin. The preferred skin bleaching agent is hydroquinone. Brighteners include but are not limited to azelaic acid, bearberry, deoxyarbuten, glycyrrhiza glabra (Licorice) root extract, kojic acid, peat extract, and their derivatives and combinations.

Proteins include animal, plant, fungi, yeast, and bacteria proteins that have skin health benefits. Exemplary proteins include but are not limited to the following: collagen, keratin, soy protein, wheat protein, bean palmitate, ascorbic acid polypeptide, the amino acids, casein, cholecalciferol polypeptide, rice protein, silk protein, gluten protein, lysine, acetyl glucosamine, actin, actizyme, albumen, conchiorin protein, corn protein, egg protein, elastin, fibronectin, gadidae protein, hemoglobin, hexapeptide-21, lactalalbumin, lupine protein, maple sycamore protein, milk protein, myristoyl pentapeptide-8, myristoyl tetrapeptide-8, oat protein, oligopeptide 10, palmitoyl hexapeptide-14, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, pea protein, potato protein, reticulin, rice bran protein, serum protein, sweet almond protein, tetrapeptide-16, vegetable protein, yeast protein, palmitoyl oligopeptide, pantothenic acid polypeptides, milk solids, sericin, albumen, amylase, amyloglucosidase, arginine, bromelain, catalase, gelatin, zein, crystallins, cytochrome C, deoxyribonuclease, gliadin, glucose oxidase, glycoproteins, lactoferrin, lactoglubulin, lactoperoxidase, lipase, nisin, oxido reductases, papain, pepsin, subtilisin, sutilains, and their combinations and derivatives.

Cleansers include agents that are used for cleaning the skin and hair by solubilizing oil and suspending soils. Cleansers may be foaming or non-foaming. Exemplary cleaners are typically a surfactant and can be characterized as nonionic, anionic, or zwitterionic.

Nonionic Surfactants. Nonionic surfactants are generally characterized by the presence of an organic hydrophobic group and an organic hydrophilic group. The length of the hydrophilic moiety can be readily adjusted to yield a water dispersible or water soluble compound having the desired degree of balance between hydrophilic and hydrophobic properties. Exemplary nonionic surfactants include the following:

-   -   Alkylpolysaccharide surfactants that include a hydrophobic group         containing from about 6 to about 30 carbon atoms and a         polysaccharide, e.g., a polyglycoside, hydrophilic group         containing from about 1.3 to about 10 saccharide units. Any         reducing saccharide containing 5 or 6 carbon atoms can be used,         e.g., glucose, galactose and galactosyl moieties can be         substituted for the glucosyl moieties. Exemplary         alkylpolysaccharide surfactants include caproyl ethyl glucoside,         caprylyl/capryl glucoside, coco-glucoside, deceth-7 glucoside,         decyl glucoside,     -   Condensation products of one mole of a saturated or unsaturated,         straight or branched chain alcohol having from about 6 to about         24 carbon atoms with from about 3 to about 50 moles of ethylene         oxide. The alcohol moiety can consist of mixtures of alcohols in         the above delineated carbon range or it can consist of an         alcohol having a specific number of carbon atoms within this         range.     -   Condensation products of one mole of saturated or unsaturated,         straight or branched chain carboxylic acid having from about 8         to about 18 carbon atoms with from about 6 to about 50 moles of         ethylene oxide. The acid can be a mixture of acids in the above         defined carbon atoms range or it can be an acid having a         specific number of carbon atoms within the range.     -   Amine oxides are tertiary amine oxides and semi-polar nonionic         surfactants corresponding to the general formula:

where the arrow=a conventional representation of a semi-polar bond; and, R¹, R², and R³ may be aliphatic, aromatic, heterocyclic, alicyclic, or combinations thereof.

Useful amine oxide surfactants are almondamidopropylamine oxide, babassuamidopropylamine oxide, behenamine oxide, cocamidopropyle amine oxide, cocamine oxide, decylamine oxide, decyltetradecylamine oxide, dihydroxyethyl alkoxyalkylamine oxides, dihydroxyalkyl alkylamine oxides, hydrogenated palm kernel amine oxide, hydrogenated tallowamine oxide, alkoxy alkylamine oxides, isostearamidopropylamine oxide, isostearamidopropyl morpholine oxide, lauramidopropylamine oxide, lauramine oxide, methyl morpholine oxide, milkamidopropyl amine oxide, minkamidopropylamine oxide, myrstamidopropylamine oxide, myrstamine oxide, myristyl/cetyl amine oxide, oleamidopropylamine oxide, oleamine oxide, olivamidopropylamine oxide, palmitamidopropylamine oxide, palmitamine oxide, sesamidopropylamine oxide, soyamidopropylamine oxide, stearamidopropylamine oxide, stearamine oxide, tallowamidopropylamine oxide, tallowamine oxide, undecylenamidopropylamine oxide, wheat germamidopropylamine oxide.

Anionic Surfactants. Anionic surfactants includes those with a negative charge on the hydrophobic group or surfactants in which the hydrophobic section of the molecule carries no charge unless the pH is elevated to neutrality or above (e.g. carboxylic acids). Carboxylate, sulfonate, sulfate and phosphate are the polar (hydrophilic) solubilizing groups found in anionic surfactants. Cations (counter ions) associated with these polar groups include sodium, lithium, potassium, ammonium, substituted ammonium, calcium, barium, and magnesium.

Anionic surfactants can be subdivided into five major chemical classes: (1) acylamino acids (and salts), such as acylgluamates, acyl peptides, sarcosinates (e.g. N-acyl sarcosinates), taurates (e.g. N-acyl taurates and fatty acid amides of methyl tauride), and the like; (2) carboxylic acids (and salts), such as alkanoic acids (and alkanoates), ester carboxylic acids (e.g. alkyl succinates), ether carboxylic acids, and the like; (3) phosphoric acid esters and their salts; (4) sulfonic acids (and salts), such as isethionates (e.g. acyl isethionates), alkylaryl sulfonates, alkyl sulfonates, sulfosuccinates (e.g. monoesters and diesters of sulfosuccinate), and the like; and (5) sulfuric acid esters (and salts), such as alkyl ether sulfates, alkyl sulfates, and the like Exemplary anionic surfactants include the following:

-   -   Linear and branched primary and secondary alkyl sulfates, alkyl         ethoxysulfates, fatty oleyl glycerol sulfates, alkyl phenol         ethylene oxide ether sulfates, the C₅-C₁₇ acyl-N—(C₁-C₄ alkyl)         and —N—(C₁-C₂ hydroxyalkyl) glucamine sulfates, and sulfates of         alkylpolysaccharides such as the sulfates of alkylpolyglucoside         (the nonionic nonsulfated compounds being described herein).         Exemplary alkyl sulfates include ammonium alkyl sulfates,         ammonium cocomonoglyceride sulfates, ammonium dimethicone         copolyol sulfate, ammonium laureth sulfates, ammonium lauryl         sulfates, ammonium myristyl sulfates, ammonium palm kernel         sulfate, diethylamine laureth sulfate, hydroxyethylbutylamine         laureth sulfate, magnesium coco-sulfate, magnesium laureth         sulfate, monoethanolamine and triethanolamine salts of coco,         laureth, and C₁₀-C₁₅ alkyl sulfates, potassium lauryl sulfate,         sodium C₁₂-C₂₀ alkyl sulfates, sodium laureth sulfates, sodium         lauryl sulfate, sodium myristyl sulfate, sodium oleth sulfate,         sodium stearyl sulfate, and sodium tallow sulfate.     -   Ammonium and substituted ammonium (such as mono-, di- and         triethanolamine) and alkali metal (such as sodium, lithium and         potassium) salts of the alkyl mononuclear aromatic sulfonates         such as the alkyl benzene sulfonates containing from 5 to 18         carbon atoms in the alkyl group in a straight or branched chain,         e.g., the salts of alkyl benzene sulfonates, such as ammonium         dodecylbenzenesulfonate.     -   Anionic carboxylate surfactants such as alkyl ethoxy         carboxylates, the alkyl polyethoxy polycarboxylate surfactants         and the soaps (e.g. alkyl carboxyls). Exemplary carboxylate         surfactants include magnesium laureth carboxylate,         monoethanolamine laureth carboxylate, sodium laureth         carboxylates, sodium pareth carboxylates, sodium cocoamide         carboxylates, and sodium trideceth carboxylates.     -   Olefin sulfonates, such as long chain alkene sulfonates, long         chain hydroxyalka sulfonates or mixtures of alkenesulfonates and         hydroxyalkane-sulfonates, sulfosuccinates, alkyl sulfates, alkyl         poly(ethyleneoxy) ether sulfates and aromatic poly(ethyleneoxy)         sulfates. Exemplary sulfonates include DEA-methylmyristate         sulfonate, magnesium lauryl hydroxypropyl sulfonate, and the         like. Exemplary sulfosuccinates include ammonium lauryl         sulfosuccinates, diammonium lauryl sulfosuccinates, dioctyl         sodium sulfosuccinate, disodum cetearyl sulfosuccinate, disodium         cocamido sulfosuccinates, disodium coco-glucoside         sulfosuccinate, disodium dimethicone copolyol sulfosuccinate,         disodium hydrogenated cottonseed glyceride sulfosuccinate,         disodium isostearyl sulfosuccinate, disodium laureth         sulfosuccinates, and the like.     -   Exemplary sarcosinates include sodium C12-C18 sarcosinates,         sodium cocoyl sarcosinate, and the like. Exemplary taurates         include sodium salts of cocoyl taurate, lauroyl taurate,         myristoyl taurate, palmitoyl taurate, and stearoyl taurate.

Zwitterionic Surfactants. Zwitterionic surfactants generally contain cationic and anionic groups which ionize to a nearly equal degree in the isoelectric region of the molecule and which can develop strong “inner-salt” attraction between positive-negative charge centers.

Zwitterionic surfactants include betaines of the general structure:

Examples of suitable betaines include almondamidopropyl betaine, apricotamidopropyl betain, avocadamidopropyl betaine, babassuamidopropyl betaine, behenamidopropyl betaine, behenyl betaine, canolamidopropyl betaine, cocamidoethyl betaine, cocamidopropyl betaine, coco-betaine, coco/oleamidopropyl betaine, decyl betaine, lauramidopropyl betaine, myristamidopropyl betaine, myristyl betaine, oleamidopropyl betaine, oleyl betaine, palmamidopropyl betaine, olivamidopropyl betaine, stearyl betaine, and the like.

Preferred cleansers include taurates, sulfates, sulfonates, carboxylates, sulfosuccinates, and sarcosinates, zwitterionic betaines, fatty acid and fatty alcohol derivatives, and alkylpolyglucoside and amine oxide surfactants. In some embodiments, the cleansers may be combined with some abrasives such as clays and sulfurs to provide light exfoliation.

Hair conditioners include agents that enhance the appearance and feel of hair by improving a property like gloss, texture, or body. Exemplary hair conditions include but are not limited to the following: lanolin, silicone, dimethicone, proteins such as amino acids, collagen, and keratin, vitamins, betaine surfactants, amine oxide surfactants, ceramide, fatty acids, eggs, milk, natural plant and animal oils, mineral oil, olive oil, polyquaternium, and their derivatives and combinations.

The skin care agents may be delivered to the skin individually or in a variety of compositions. For example, the skin care agents may be part of a water-thin liquid, thickened liquid, lotion, cream, gel, emulsion or structured liquid, paste, wax, or solid composition. When formulated as a composition, the skin care agents may be present with other skin care agents or additional ingredients that impart a skin care benefit or help in applying the skin care agent. Exemplary additional ingredients include anticaking agents, antifoaming agents, binders, buffers and pH adjusters, dyes, essential oils, and fragrances, chelating agents, corrosion inhibitors, emulsifiers, emulsion stabilizers, film formers, plasticizers, preservatives, propellants, solvents, foaming agents, hydrotropes, UV light absorbers, thickeners, and the like. When the skin care agents are combined with these additional ingredients, they can form exemplary compositions such as shampoos, conditioners, treatments, cleansers, soaps, toners, lotions, moisturizers, masks, serums, gels, scrubs, exfoliants, and wax blocks.

In some embodiments, the skin care agent or skin care compositions are available to users as over-the-counter (“OTC”) products, meaning that they are available to users without a doctor's prescription. In some embodiments, the skin care agent or skin care compositions are available to users through a doctor's prescription.

A preferred skin care composition includes a combination of proteins, skin conditioners, moisturizers, and antioxidants. Exemplary proteins include sericin, collagen, keratin, amino acids, hexapeptide-21, myristoyl pentapeptide-8, myristoyl tetrapeptide-8, oligopeptide 10, palmitoyl hexapeptide-14, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, tetrapeptide-16, and derivatives and combinations thereof. Exemplary skin conditioners include hyaluronic acid, alpha hydroxyl acids (i.e.: glycolic acid, lactic acid, ascorbic acid), polyhydroxy acids (i.e.: gluconolactone, lactobionic acid), beta hydroxyl acid, and derivatives and combinations thereof. Exemplary moisturizers include glycerin, dimethicones, triglycerides, natural oils (i.e., olive oil, jojoba oil, soybean oil, coconut oil), silicone, dormin, shea butter, lanolin, glycerides, coco butter, and derivatives and combinations thereof. Exemplary antioxidants include retinol, retinyl palmitate (vitamin A), ascorbic acid (vitamin C), tocopheryl acetate (vitamin E), feverfew, hydroxytyrosol, CoQ10, resveratrol, sirtuins, carotenoids, alpha lipoic acid and derivatives and combinations thereof.

Another preferred skin care composition includes the following materials: water, caprylic/capric triglyceride, Butyrospermum Parkii (shea) butter, cyclopentasiloxane, glycerin, glyceryl stearate, butylene glycol, stearic acid, Carthamus Tinctorius (Safflower) Seed Oil, stearyl alcohol, polysorbate 60, cyclohexasiloxane, sorbitol, dimethicone, dimethicone/vinyl dimethicone crosspolymer, phenoxyethanol, fragrance, caprylyl glycol, retinol, polysorbate 20, ethylhexylglycerin, Glycyrrhiza Glabra (Licorice) Root Extract, BHT, disodium EDTA, dipotassium glycyrrhizate, hexylene glycol, tocopheryl acetate, triethanolamine, carbomer, bisabolol, glyceryl acrylate/acrylic acid copolymer, sodium hyaluronate, and dye.

Another preferred skin care composition includes the following materials: cyclopentasiloxane, isododecane, dimethicone/bis-isobutyl PPG-20 crosspolymer, cyclohexasiloxane, ethoxydiglycol, ascorbic acid, caprylic/capric triglyceride, kojic acid, azelaic acid, ethylhexyl hydroxystearate, polysilicone-11, Syringa Vulgaris (Lilac) Leaf cell culture extract, and maltodextrin.

Methods of Using the Exfoliation Tool and the Selected Skin Care Agents

The exfoliation tool and selected skin care agents can be used to treat any skin surface on a human. Exemplary skin surfaces can include the scalp, the face, neck, and decolletage, and the body, such as the back, arms, legs, hands, feet, chest, stomach, and buttocks. The exfoliation tool and skin care agents can be used to treat sensitive skin such as that found on the face, neck, and decolletage as well as tough skin such as that found on knees, elbows, hands, and feet. Further, the exfoliation tool and selected skin care agents may be used to treat a wide variety of people of all ages, skin colors, and skin types. For example, the exfoliation tool and selected skin care agents can be used to treat people from infants, to children, to teenagers, to adults, and the elderly. The exfoliation tool and selected skin care agents can be used to treat a variety of skin colors including fair, olive, tan, brown, and black, and all of the variations in between. Finally, the exfoliation tool and selected skin care agents can be used to treat a variety of skin types including dry, normal, oily, sensitive, and acne-prone skin, and combinations of these.

The exfoliation tool and selected skin care agents can be used to treat, maintain, or improve a variety of skin care features or ailments such as skin health and integrity, skin healing, scalp irregularities or ailments, and visual or cosmetic irregularities or ailments.

The exfoliation tool and selected skin care agents can be used to maintain skin health by improving the skin integrity and water retention. Healthy skin retains water well compared to dry skin. When the exfoliation tool and selected skin care agents are used as directed for a period of time, the skin should have an improvement in transepidermal water loss (TEWL).

The exfoliation tool and selected skin care agents can be used to maintain a healthy scalp, or treat or improve scalp irregularities and ailments such as dandruff, dry scalp, baldness, hair thinning, and alopecia. The exfoliation tool and selected skin care agents can also be used to improve the health, quality, look or feel of hair by maintaining a healthy scalp, or treating the scalp. For example, the exfoliation tool and selected skin care agents can be used to improve hair texture, hair breakage, hair volume, and hair shine.

Finally, the exfoliation tool and selected skin care agents can be used to maintain healthy skin, or treat or improve skin irregularities and ailments such as scarring, sun damage, fine lines, deep lines or wrinkles, acne, blocked pores, blackheads, dry skin, oily skin, birthmarks, irregular skin tone or color, pore size, stretch marks, uneven texture, age spots, lack of firmness or skin tightness, cellulite, veins, fungus, rashes, keritosis pilaris, hair growth in the case of areas where hair growth is undesired, irritation or skin sensitivities, redness, puffiness or bloating, eczema, psoriasis, and rosacea.

In some embodiments, the exfoliation tool and the selected skin care agents can be used as part of a skin care regimen where particular agents are used together with the exfoliation tool. For example, when treating the scalp, it may be beneficial to use the exfoliation tool with at least one agent that is directed to maintaining, treating, or improving scalp health and hair loss such as an antidandruff agent, a cleanser, a moisturizer, or a hair conditioner. Preferred skin care agents for the scalp include minoxidyl, coal tar, salicylic acid, selenium sulfide, sulfur, zinc pyrithione, and their derivatives and combinations. In some embodiments, it may be beneficial to use the exfoliation tool with an agent that is part of a shampoo, conditioner, hair mask, scalp treatment, pre-treatment, or other treatment or tonic composition.

When treating skin on the face, neck, and decolletage, it may be beneficial to use the exfoliation tool with at least one agent that is directed to maintaining, treating, or improving skin health such as an abrasive, antiacne agent, antifungal agent, antimicrobial agent, antioxidant, toner, moisturizer, skin conditioner, humectant, emollient, skin bleaching or lightening agent, protein, or cleanser. Preferred skin care agents for the face, neck, and decolletage include retinol, sericin, hexapeptide-21, myristoyl pentapeptide-8, myristoyl tetrapeptide-8, oligopeptide 10, palmitoyl hexapeptide-14, palmitoyl oligopeptide, palmitoyl tetrapeptide-7, tetrapeptide-16, hyaluronic acid, alpha hydroxyl acids (i.e.: glycolic acid, lactic acid, ascorbic acid), polyhydroxy acids (i.e.: gluconolactone, lactobionic acid), beta hydroxyl acid, glycerin, silicone, jojoba oil, dormin, shea butter, dimethicones, olive oil, soybean oil, lanolin, glycerides, coco butter, coconut oil, retinyl palmitate (vitamin A), caffeine, ascorbic acid (vitamin C), tocopheryl acetate (vitamin E), feverfew, hydroxytyrosol, CoQ10, resveratrol, sirtuins, carotenoids, alpha lipoic acid, hydroquinone, benzoyl peroxide, sulfur, salicylic acid, actizyme, and derivatives and combinations of these. In some embodiments, it may be beneficial to use the exfoliation tool with an agent that is part of a cleanser, toner, moisturizer, exfoliant, mask, or serum composition. Similar agents and compositions can be used for treating body skin such as on the arms, legs, hands, feet, back, stomach, and buttocks. The agents and compositions can be used in varying concentrations and potentially higher concentrations on body skin versus the sensitive skin such as the face, neck, and decolletage. Additional preferred skin care agents include calcium undecylenate, ketoconazol, povidone-iodine (PVP-iodine), tea tree oil, undecylenic acid, zinc undecylenate, lower chain (C₁-C₄) alcohols, quaternary ammonium compounds such as benzalkonium chloride and benzethonium chloride, clindamycin, methylbenzethonium chloride, hydrogen peroxide, phenols, triclosan, povidone-iodine (PVP-Iodine), and their derivatives and combinations.

The following table describes some exemplary method embodiments. This table is designed to be exemplary only and not limiting:

TABLE A Exemplary Method Embodiments Step 1 Step 2 Step 3 Step 4 Step 5 Step 6 Step 7 Step 8 Face, Neck, and Décolletage Treatment Cleanser Exfoliation Tool Exfoliation Cleanser Tool Cleanser Toner Exfoliation Tool Cleanser Exfoliation Toner Tool Cleanser Toner Moisturizer Sunscreen Exfoliation Tool Cleanser Toner Exfoliation Moisturizer Sunscreen Tool Cleanser Toner Exfoliation Moisturizer Tool Cleanser Toner Exfoliant Exfoliation Tool Cleanser Toner Moisturizer Sunscreen Cleanser Toner Exfoliation Moisturizer Tool Body Treatment Cleanser Exfoliation Tool Exfoliation Cleanser Tool Cleanser Exfoliation Moisturizer Tool Cleanser Exfoliation Treatment Moisturizer Tool Cleanser Exfoliation Exfoliant Tool Cleanser Exfoliant Exfoliation Moisturizer Tool Cleanser Exfoliant Exfoliation Moisturizer Sunscreen Tool Scalp Treatment Shampoo Exfoliation Tool Exfoliation Shampoo Tool Shampoo Exfoliation Conditioner Tool Pre- Shampoo Exfoliation Conditioner Treatment Tool Scalp Shampoo Exfoliation Conditioner Treatment Tool Hair Mask Exfoliation Shampoo Conditioner Tool Shampoo Exfoliation Conditioner Treatment Tool Exfoliation Shampoo Conditioner Tool Exfoliation Shampoo Treatment Conditioner Tool

The steps in Table A can be performed in any order. Some steps can be combined into a single skin care composition (such as a combination of moisturizer and sunscreen). Finally, the steps can take place over time. For example, some steps can be performed in the morning and other steps can be performed in the evening. Some steps can be performed daily and other steps can be performed less frequently, such as weekly or monthly.

EXAMPLES

The present disclosure may be better understood with reference to the following example. Thus example is intended to be representative of specific embodiments of the disclosure, and is not intended as limiting the scope of the disclosure.

Example 1

Example 1 determined the effect of the exfoliation tool on skin's water balance, transepidermal water loss (TEWL), corneometry, and skin elasticity. Also evaluated were the visual effects on skin smoothness, softness, and texture. The example compared a skin care regimen of a mask, toner, day cream, serum capsule, and night cream both with and without the use of an exfoliation tool in improving skin appearance.

Thirty female subjects over the age of 35 were enrolled in an 8-week, single site, investigator-blinded study. Twenty subjects used a skin care treatment regimen consisting of a cleansing mask, toner, day cream, serum capsules, and night cream. In addition, these subjects also used an exfoliation tool nightly (every other night for the first 2 weeks, then nightly thereafter). Ten subjects used only the skin care regimen without the exfoliation tool. Investigator assessments, subject assessments, photography, and noninvasive assessments were used to evaluate the effectiveness of the two treatment arms. Subjects were evaluated at the following time points: baseline, 5 minutes, week 2, week 4, and week 8.

Subjects using the exfoliation tool were instructed to use the cleansing mask, toner, and day cream in the morning and use the cleansing mask, toner, exfoliation tool, serum capsules, and night cream in the evening in that order. Subjects that did not use the exfoliation tool followed the same protocol but did not use the exfoliation tool in the evening.

Subject were given the following directions for the products and the exfoliation tool if applicable:

Product 1 Cleansing Mask: Using wet fingertips, gently and evenly massage a quarter-sized amount onto dry skin. Ensure entire face is covered with a thin coat of product, avoiding contact with eyes. Allow product to dry completely, about 2-3 minutes. Rinse thoroughly; pat dry.

Product 2 Toner: Shake well before use. Apply evenly to entire face with a gauze pad, avoiding the eye area. Do not rinse off. Allow to dry.

Product 3 Day Cream SPF 30: Apply a dime-sized amount over entire face every morning. Avoid eye area.

Product 4 Serum Capsules: Open capsule and apply serum to the entire face evenly. Use only in the evening.

Product 5 Night Cream: Apply a dime-sized amount over entire face every evening.

Exfoliation Tool: For Week 1 and Week 2, use tool every other night after Products 1 and 2. For Weeks 3-8, increase to nightly use as tolerated. With moderate and comfortable pressure, roll the tool over entire face and neck 4-10 times. For best results, divide the face into sections (forehead, right side, left side, chin, neck) and treat each section before continuing onto the next. Change the orientation of rolling over each section to ensure complete surface coverage. After rolling, apply Product 4 (one Serum Capsule) over entire face and neck and follow with Product 5 (Night Cream).

Subjects were evaluated by collecting observations at baseline, 5 minutes, week 2, week 4, and week 8. A dermatologist investigator performed all visual assessments. The parameters evaluated consisted of: investigator evaluations, subject evaluations, subject marketing questionnaire, noninvasive assessments (TEWL, corneometry, elasticity), and photography. The rating scale for evaluation for all subject and investigator assessments was: 0=none, 1=minimal, 2=mild, 3=moderate, 4=severe.

After the 8-week study, the following results or observations were made:

-   -   The corneometry difference from baseline showed that there was         no statistically significant benefit in skin moisturization with         the exfoliation tool in addition to the skin care products         versus using the skin care products alone. Corneometry is a         measure of the conductivity of the skin utilizing water as the         conductor. More water in the skin indicates superior hydration,         thus a higher corneometry measurement is more favorable.     -   Both groups (with and without the exfoliation tool) showed a         statistically significant improvement in skin moisturization at         weeks 2, 4, and 8. This finding points to the ability of the         skin care regimen to significantly improve skin moisturization.         It is worthwhile noting that the addition of the exfoliation         tool to the skin care products produced highly statistically         significant (p<0.001) improvement in moisturization at weeks 2         and 4, which was not the case with the skin care product alone         group.     -   The corneometry numbers were noticeably higher in the group that         used the exfoliation tool, especially at week 4. This might         directionally point to the value of the exfoliation tool in         improving skin hydration.     -   The investigator noted improvements within both groups over the         8 weeks. At week 2, the investigator noted a statistically         significant improvement in skin texture in all subjects. A         statistically significant improvement was seen in fine lines,         skin texture, and overall appearance with both groups at week 4.         Finally, at week 8, statistically significant improvement was         seen in fine lines, skin texture, and overall appearance. Thus,         the skin care regimen was successful in improving skin         appearance.     -   The investigator direct comparison did not show any         statistically significant differences between the exfoliation         tool plus skin care products and the skin care products group         alone. This could be due to the small sample size or the short         study period. It is possible that new collagen production from         the exfoliation tool might take longer than 12 weeks.     -   No changes in skin elasticity were seen between the exfoliation         tool plus skin care product group and the skin care product         group alone. Skin elasticity is more variable in its         interpretation than the corenometry measurements. Three         elasticity measurements were obtained. The elasticity         measurements were obtained with a suction cup that stretched the         skin into the cup under negative vacuum pressure. Once the skin         was stretched into the top of the cup, such that a light beam at         the top of the cup was broken, the negative vacuum pressure was         discontinued and the skin relaxed. This sequence of events was         repeated three times. With each subsequent iteration of the         suction and relaxation, the skin becomes stretchier and         stretchier and the numbers decreased. Thus, the skin becomes         more elastic with stretching.     -   There was no intragroup difference in skin elasticity between         the exfoliation tool plus skin care product group and the skin         care product group alone. However, it is important to look at         the absolute numbers, since the sample size was small. The skin         elasticity numbers were higher in the exfoliation tool group         than in the skin treatment alone group. This means that it took         more energy to deform the skin of the subjects that used the         exfoliation tool, which can be interpreted as firmer skin         possibly due to a higher water content.     -   No statistically significant differences in skin elasticity were         seen on direct comparison between the exfoliation tool plus skin         care products and skin care products alone group. Again, it is         important to note that the elasticity measurements were higher         at week 8 in the group that used the exfoliation tool plus the         skin care products. This means that the exfoliation tool         improved skin firmness directionally.     -   The subject difference from baseline was used to analyze         intergroup changes. No statistically significant changes were         seen between subject assessments in the exfoliation tool plus         skin care products group or the skin care products alone group         at weeks 2, 4, or 8.     -   The intragroup longitudinal assessment demonstrated that while         both groups of subjects assessed improvement, the improvement         was rated more dramatic in the group that used the exfoliation         tool and skin care products as opposed to the skin care products         alone group. At week 2, there was a statistically significant         improvement in skin softness (p=0.032), skin radiance (p=0.008),         skin evenness (p=0.002), pore appearance (p=0.012), wrinkles         (p=0.006), fine lines (p=0.009), and brown spots (p=0.009). This         is improvement in more attributes than the skin care product         alone group. Statistically significant improvement was seen in         softness, radiance, pores, fine lines, and brown spots with the         exfoliation tool at week 2, which was not the case with the skin         care products alone. However, the skin care products also         elicited excellent ratings by the subjects. There was         statistically significant improvement in evenness (p=0.011) and         wrinkles (p=0.022) at week 2. By week 4, there was statistically         significant improvement in both groups in terms of radiance,         evenness, pores, and wrinkles. At week 4, the exfoliation tool         plus product group outperformed the product group alone with         additional statistically significant improvement in fines lines         (p<0.001), brown spots (p<0.001), and dryness (p=0.047). The         subject assessed differences were the greatest at week 8. The         exfoliation tool group assessed statistically significant         improvements in radiance, evenness, pore appearance, wrinkles,         fine lines, brown spots, and dryness. No statistically         significant increase in irritation was noted pointing toward an         excellent tolerability profile for the exfoliation tool. The         subjects who used the skin care products alone assessed         statistically significant improvement in radiance and evenness.         This means that the use of the exfoliation tool added an         incremental benefit in pore appearance, wrinkles, fine lines,         brown spots and dryness.     -   The direct comparison results were similar to the difference         from baseline results and failed to show much statistically         significant intergroup difference. It appears that with the         study design and small sample size, the longitudinal analysis         was best able to elicit the subtle differences between the two         study groups.     -   No statistically significant differences in TEWL were seen         between the exfoliation tool plus study products group and the         study products alone group.     -   TEWL is a measure of the water leaving the skin. Indeed, TEWL         was increased in the group using the exfoliation tool. This         means that the exfoliation tool did penetrate the skin barrier         and allow more water to escape. A statistically significant         increase in water loss was seen with the exfoliation tool users         as compared to baseline at week 2 (p=0.032) and week 4         (p=0.013). The change was not statistically significant at week         8. No statistically significant changes in TEWL were seen in the         product use alone group. The TEWL evaluation demonstrates the         ability of the exfoliation tool to produce a physiologic effect         on the skin.     -   No statistically significant differences in TEWL were seen in         the intergroup direct comparison analysis. This means that the         exfoliation tool did not damage the skin in a negative fashion.

The above specification, examples and data provide a complete description of the use of the disclosed methods and skin care agents. Since many embodiments can be made without departing from the spirit and scope of the disclosure, the invention resides in the claims. 

1-20. (canceled)
 21. A skin care regimen comprising: a cleanser selected from a foaming cleanser, a non-foaming cleanser, or a clay-containing cleanser; an exfoliation tool; a first skin care composition, wherein the first skin care composition comprises: cyclopentasiloxane, dimethicone, polysilicone-11, ethylhexyl hydroxystearate, palmitoyl hexapeptide-14, retinyl palmitate, hydroxyapatite, ethoxydiglycol, and optional additional ingredients; and instructions for use.
 22. The skin care regimen of claim 21 further comprising a toner, wherein the toner comprises witch hazel and alcohol.
 23. The skin care regimen of claim 21, wherein the exfoliation tool comprises a handle and a head, the head comprising a roller, a collar, and a plurality of acupuncture needles located on the roller.
 24. The skin care regimen of claim 23, wherein the needles on the exfoliation tool are from about 0.1 mm to about 0.5 mm in length.
 25. The skin care regimen of claim 21 further comprising a second skin care composition.
 26. The skin care regimen of claim 25, wherein the second skin care composition comprises agents selected from the group consisting of moisturizers, skin conditioners, humectants, emollients, proteins, hair conditioners, and combinations thereof.
 27. The skin care regimen of claim 21, wherein the instructions for use direct a user to follow the steps in order:
 1. wet skin, massage cleanser evenly over face, rinse, and pat dry;
 2. contact the exfoliation tool to a user's skin divided into sections, roll the exfoliation tool across the user's skin 4 to 10 times using moderate and comfortable pressure, and optionally change the orientation of rolling over each section to ensure complete surface coverage; and
 3. apply the first skin care composition.
 28. The skin care regimen of claim 27, wherein the user's skin is selected from the group consisting of scalp, face, neck, décolletage, body, back, arms, legs, hands, feet, chest, stomach, and buttocks.
 29. The skin care regimen of claim 27, wherein the instructions further direct the user to apply a second skin care composition.
 30. The skin care regimen of claim 22, wherein the instructions for use direct a user to follow the steps in order:
 1. wet skin, massage cleanser evenly over face, rinse, and pat dry;
 2. apply the toner with a pad over clean face and allow to dry;
 3. contact the exfoliation tool to a user's skin divided into sections, roll the exfoliation tool across the user's skin 4 to 10 times using moderate and comfortable pressure, and optionally change the orientation of rolling over each section to ensure complete surface coverage; and
 4. apply the first skin care composition.
 31. The skin care regimen of claim 30, wherein the user's skin is selected from the group consisting of scalp, face, neck, décolletage, body, back, arms, legs, hands, feet, chest, stomach, and buttocks.
 32. The skin care regimen of claim 30, wherein the instructions further direct the user to apply a second skin care composition.
 33. A method of improving or maintaining skin health comprising: cleansing skin with a cleanser selected from a foaming cleanser, a non-foaming cleanser, or a clay-containing cleanser; treating the skin with an exfoliation tool; and applying a first skin care composition, wherein the first skin care composition comprises: cyclopentasiloxane, dimethicone, polysilicone-11, ethylhexyl hydroxystearate, palmitoyl hexapeptide-14, retinyl palmitate, hydroxyapatite, ethoxydiglycol, and optional additional ingredients.
 34. The method of claim 33 further comprising applying a toner, wherein the toner comprises witch hazel and alcohol.
 35. The method of claim 34, wherein the toner is applied to the skin before treating the skin with the exfoliation tool.
 36. The method of claim 33, wherein the exfoliation tool comprises a handle and a head, the head comprising a roller, a collar, and a plurality of acupuncture needles located on the roller.
 37. The method of claim 36, wherein the needles on the exfoliation tool are from about 0.1 mm to about 0.5 mm in length.
 38. The method of claim 33, further comprising a second skin care composition.
 39. The method of claim 38, wherein the second skin care composition comprises agents selected from the group consisting of moisturizers, skin conditioners, humectants, emollients, proteins, hair conditioners, and combinations thereof.
 40. The method of claim 38, wherein the second skin care agent is applied to skin after treating the skin with the exfoliation tool.
 41. The method of claim 38, wherein the second skin care agent is applied to skin after applying the first skin care composition. 